Holy crap on a cracker and others...

요즘 "The big bang theory" 를 아주 재미있게 보고 있다.

2x06

holy crap on a cracker : Emphatic form of "holy crap"

pick someone's brain
    obtain ideas or informations from another person
      as in "I'm out of ideas for this method. Can I pick your brain?"
      often used in the form of "Let me pick your brain."

2x07

knuckle under : to yield to pressure, give in
    Penny : Knuckle under my ass.

Just remember, with great power, comes great responsibility.

2x09

Since Lenerd seems to be dropping the conversational ball, I think I just have to pick it up.

If you failed this relationship, and history suggests you will.

You're deemed unfit and I hearby relieve you of your command.